From recruiting study participants to making sure that everybody shows up for their appointment when they’re supposed to, putting together a clinical trial is certainly no walk in the park. In fact, today’s clinical trials have become so complex that there is almost no way to track everything by hand. Fortunately, the best clinical trial management system (CTMS) software has come a long way in its functionality. Using modern CTMS software feels a bit like using a CRM, but CTMS platforms are designed with research organizations in mind. Typically, a top-flight CTMS includes modules for regulatory compliance, project management, recruiting, document scanning, and data capture.
With that said, some CTMS vendors have recently started packing in accounting modules, financial dashboards, and more advanced reporting capabilities. As companies continue to tap the power of the cloud, CTMS software has also started going mobile. Although choosing a clinical trial management system ultimately comes down to figuring out which one your team members will actually use, the list below provides ten outstanding options to consider.
Castor Electronic Data Capture (EDC) is built for contract research organizations (CROs), large healthcare systems, biotechnology companies, and medical device suppliers. The software integrates smoothly with other healthcare data systems, and Castor’s API makes it easy to build custom integrations if necessary. Castor EDC also has a large library of pre-built templates that can each save you a ton of time, and the company provides one-on-one customer support to make sure your team gets the most of every module.
ClinPlus CTMS, a premium offering from Anju Software, includes modules for electronic data capture, statistical reporting, medical coding, and data disclosure. The BioStats analysis platform inside of ClinPlus CTMS uses a robust library of tables, listings, and figures to help your organization create engaging visuals and insightful reports. Since ClinPlus CTMS supports Rich Text Format, it’s easy to transfer your data to popular word processors such as Microsoft Word, Google Docs, and Apple Pages. This software suite’s analytical capabilities are top-notch, and the simple user interface makes manual data entry a breeze.
Designed for smartphones, tablets, and other mobile devices, Encapsia aims to be an end-to-end, cloud-based solution for research organizations of all sizes. The platform automatically updates charts and graphs as soon as you enter new data, and Encapsia’s eSource feature lets you directly capture trial results on your tablet.
Encapsia users also get full access to the company’s Home Visit app. Engineered for organizations that conduct a lot of offsite trials, the Home Visit app lets your staff members easily upload photographs and other multimedia, validate data recordings instantly, and customize standard template forms. Furthermore, the Home Visit app has full offline functionality and automatically syncs data to the cloud when a user regains their internet connection. If you’re looking for a software vendor that has its eyes on the future of CTMS, then you’ll probably be very impressed with Encapsia.
Although Target Health has been offering serious CTMS solutions for academic studies and medical device trials since the mid-1990s, the company’s biggest impact over the last several years has been in the pharmaceutical industry. Target Health’s e*Pharmacovigilance suite empowers biotechnology companies to monitor study participants for Serious Adverse Events (SAEs) during a trial, and this module integrates with Target e*studio to auto-populate regulatory forms with a participant’s data if they experience an SAE. Overall, Target Health makes it easy to use the features you need without paying for add-ons that you know you’ll never use.
Built by healthcare IT firm Bio-Optronics, Clinical Conductor CTMS is one of the best solutions available for companies that run multisite trials and need to share data across many locations. Clinical Conductor’s finance suite really sets it apart from the competition, and this CTMS is one of the goto solutions for biotech firms around the world. CCText, Clinical Conductor’s patient compliance application, gives your recruiting team a simple way to remind new trial participants of their appointment date, boost patient retention with SMS messaging, and even recruit existing participants to new trials. The complete CC Trial Suite has eight apps in total, and each one packs a ton of features into a very clean user interface on both ends. From electronic consent forms to world-class document management capabilities, this CTMS platform simply has it all.
As one of the newer CTMS vendors on the block, Medrio has a reputation for providing excellent support and a great user experience for both clinicians and trial participants. Medrio’s all-in-one Decentralized Trials platform, which combines the company’s EDC, eConsent, ePro, and Direct Data Capture services into a single interface, is trusted by CROs large and small. Rather than focusing on fancy graphics or complicated features, Medrio’s engineers put most of their time into making sure that organizations can go from research idea to trial completion as fast as possible.
RealTime CTMS has some pretty nifty integrations. If your organization already uses Mailchimp to send e-mails or Twilio to send SMS reminders to study participants, then you won’t need to purchase RealTime’s separate RText module with your CTMS subscription. For large companies that need to manage financial information from multiple research sites, the RealTime Enterprise package features a centralized accounting system to help you track trial expenses and stay within your company’s budget. Overall, RealTime CTMS is one of the best full-stack options available.
Along with standard CTMS features like task management dashboards and calendar integrations, Ripple CTMS offers a unique analytics module that gives your organization a comprehensive overview of each trial participant. The front end of the analytics module monitors recruiting metrics, and the back end tracks your organization’s patient funnel all the way through your study’s screening and enrollment phases. With intuitive visualization tools like progress bars and line graphs, Ripple’s project dashboard gives you a quick overview of which team members are responsible for which tasks. With Ripple, it’s easy to delegate recruiting assignments to your team with only a few clicks and freely update your study’s data fields as they change.
StudyPal’s elaborate legal compliance module is perfect for organizations that need to navigate complex regulatory landscapes. The mobile app has a dynamic interface that always gives you enough information to make a decision but not so much that you get distracted, and managers love StudyPal’s visual workflow. If your team loves to map out study protocols with flowcharts and mind maps, then they’re sure to love StudyPal.
OpenClinica has a definitive edge over other CTMS suites when it comes to automated reporting features. Instead of using spreadsheets and CSV files to store data from your trial, OpenClinica’s reporting engine has a drag-and-drop interface that lets you customize your reporting dashboards and choose which types of events you’d like to track. On top of its stellar reporting module, OpenClinica has some killer randomization features that make it possible to create your study’s protocols in minutes. You can not only use OpenClinica’s embedded randomization algorithms to group participants by traditional variables like age or sex, but you can also segment participants by user-defined variables. For organizations that need to run a series of blinded trials, OpenClinica really delivers.
Bonus tool: actiTIME
As one of the most popular timesheet applications in the world, actiTIME is a natural fit for organizations that need a streamlined CTMS. With attractive Kanban boards, automated time tracking, an outstanding API, and a slew of integrations, actiTIME helps research teams of all sizes meet regulatory deadlines with ease. If you’re looking for an affordable, customizable add-on to one of the other solutions above, then actiTIME is truly a no-brainer.